KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBR1
All Species:
16.36
Human Site:
Y675
Identified Species:
36
UniProt:
Q16650
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16650
NP_006584.1
682
74053
Y675
C
A
K
D
I
S
G
Y
Y
G
F
Y
S
H
S
Chimpanzee
Pan troglodytes
XP_526157
702
74704
Y695
T
S
K
G
M
G
G
Y
Y
A
F
Y
T
T
P
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
Y730
T
S
K
G
M
G
G
Y
Y
A
F
Y
T
T
P
Dog
Lupus familis
XP_545492
682
73929
Y675
C
A
K
D
L
G
G
Y
Y
G
F
F
S
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64336
681
73923
Y674
C
A
K
D
I
G
G
Y
Y
G
F
Y
S
H
S
Rat
Rattus norvegicus
Q5I2P1
517
57726
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
Chicken
Gallus gallus
Q9PWE8
521
58384
V514
S
V
H
G
V
G
M
V
P
E
W
S
E
N
S
Frog
Xenopus laevis
P79944
692
75925
Y685
D
A
T
K
G
L
G
Y
Y
S
F
Y
S
S
S
Zebra Danio
Brachydanio rerio
Q9IAK8
492
55218
M485
T
V
H
S
V
S
I
M
H
D
W
N
E
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
H939
S
I
N
N
M
L
C
H
G
Q
S
Y
P
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
46.8
99.2
N.A.
99.1
24.6
N.A.
30.3
24.4
50
25.5
N.A.
N.A.
N.A.
N.A.
26.7
Protein Similarity:
100
64
60.5
99.5
N.A.
99.2
37.2
N.A.
38.1
36.5
65
37.5
N.A.
N.A.
N.A.
N.A.
40.7
P-Site Identity:
100
40
40
80
N.A.
93.3
0
N.A.
0
6.6
53.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
60
60
93.3
N.A.
93.3
0
N.A.
0
26.6
53.3
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
0
19
0
0
0
10
10
% A
% Cys:
28
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
28
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
55
10
0
0
0
% F
% Gly:
0
0
0
28
10
46
55
0
10
28
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
10
10
0
0
0
0
28
0
% H
% Ile:
0
10
0
0
19
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
46
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
28
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
10
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
19
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
19
0
10
0
19
0
0
0
10
10
10
37
10
55
% S
% Thr:
28
0
10
0
0
0
0
0
0
0
0
0
19
19
0
% T
% Val:
0
19
0
0
19
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
55
0
0
55
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _